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Rediscovering Cancer: From Mechanism to Therapy

Rediscovering Cancer: From Mechanism to Therapy

Autor:

Editorial:
Apple Academic Press Inc. (Estados Unidos)

Año de edición:

ISBN:
9781771886901

Páginas:
625

AR$ 12040.00
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Descripción

This volume presents a snapshot of some of the most important ongoing research in cancer. With cancer as the second leading cause of death worldwide, extensive research is going on globally to decipher the molecular mechanism underlying cancer that will help in finding better targets for drug therapy. The book brings together new research on molecular mechanism and cancer therapeutics in one place. With chapters from experts in their respective fields, chapters cover molecular mechanisms, etiology, prognosis, detection, and treatment of cancer. Emphasis has been given to the intricate mechanism behind the deregulation of cell division, disruption of cell cycle check points, mutation in oncogenes and tumor suppressor genes, apoptosis, and erratic cell signaling. The book discusses in detail topics such as angiogenesis and tumor microenvironment, which are increasingly receiving attention, especially in the field of neoplastic vascularization and metastasis. The book also includes chapters detailing the current understanding and the future perspective of cancer stem cells.

Más detalles ↓

Rediscovering Cancer: From Mechanism to Therapy also includes some recent research on the therapeutic aspects of cancer. Chapters related to immunotherapy, chemotherapy, and use of chitosan-based nanoparticles for cancer therapy are included, with emphasis on preventive measures for cancer. 
 
Overall, this informative volume covers the present knowledge and future direction on the field of cancer research.
 
CONTENTS:
Preface
 
PART I: MOLECULAR MECHANISMS UNDERLYING INITIATION, PROMOTION, AND PROGRESSION OF CANCER
1. Genetic Instability in Cancer
Gloria Ravegnini, Patrizia Hrelia, and Sabrina Angelini
 
2. Oncogenesis and Telomerase Activity in Cancer
Sutapa Mukherjee, Madhumita Roy, and Jaydip Biswas
 
3. Cell Cycle Checkpoints in Cancer
Sreeparna Chakraborty and Abhik Sen
 
4. Angiogenesis, Its Importance and Implication in Tumor Growth and Progression and in Anticancer Therapy: An Update
Chandrani Sarkar and Debanjan Chakroborty
 
5. The Tumor Microenvironment and Metastasis
Sonia Chadha
 
6. Apoptosis: A Regulatory Mechanism in Cancer
Sutapa Mukherjee, Apurba Mukherjee, Souvick Biswas, and Madhumita Roy
 
7. Cytoplasmic Signaling Circuitry: An Important Trait of Cancer
Subhra Dash, K. Lohitesh, and Sudeshna Mukherjee
 
PART II: CANCER ETIOLOGY: PHYSICAL, CHEMICAL, ENVIRONMENTAL FACTORS, AND GENETIC SUSCEPTIBILITY
8. Cancer: An Overview of Risk Factors
Sayali Mukherjee and Shabana Siddique
 
9. Single Nucleotide Polymorphisms as Susceptibility Markers for Cancer
Suresh Kumar Yadav and Somali Sanyal
 
PART III: CANCER PREVENTION AND CONVENTIONAL THERAPIES
10. Dietary Phytochemicals in the Prevention and Therapy of Cancer: Modulation of Molecular Targets
Shamee Bhattacharjee
 
11. Health Benefits and Preventive Effects of Common Beverages in Cancer
Vivek Kumar Gaur, Sanjay Gupta, and Janmejai Kumar Srivastava
 
12. Cancer Chemotherapy
Sonal Srivastava, Sakshi Mishra, Jayant Dewangan, Aman Divakar, Prabhash Kumar Pandey, and Srikanta Kumar Rath
 
PART IV: NOVEL THERAPEUTIC APPROACHES FOR CANCER
13. Non-Coding RNAs : The New Reins in Malignancies
Deba Prasad Mandal
 
14. Epigenetics in Cancer Prevention and Therapy: Role of Phytochemicals
Sajid Khan, Samriddhi Shukla, and Syed Musthapa Meeran
 
15. Cancer Stem Cell: Current Understanding and Future Perspectives
Sonal Srivastava, Jayant Dewangan, Divya Tandon, and Srikanta Kumar Rath
 
16. Tumor Microenvironment and Cancer Stem Cells: Therapeutic Potential of Epigenetic Inhibitors to Target CSCs
Anup Kumar Singh, Priyank Chaturvedi, and Dipak Datta
 
17. Nanoparticles in Cancer Therapy
Madhuchanda Banerjee
 
18. Cancer Immunotherapy: Extending New Horizons in Cancer Treatment
Deba Prasad Mandal

Catalogado en

Medicina / Medicina - Oncología

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